Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
Q8N3Z3
UPID:
GTPB8_HUMAN
Alternative names:
-
Alternative UPACC:
Q8N3Z3; A6NE99; A6NN11; A8K0P6; Q5I0Y4
Background:
GTP-binding protein 8 plays a crucial role in cellular processes by acting as a molecular switch. It cycles between an active GTP-bound state and an inactive GDP-bound state, influencing various signaling pathways and cellular functions. This protein's precise mechanisms and interactions within the cell remain a subject of ongoing research, highlighting its potential in unraveling new biological insights.
Therapeutic significance:
Understanding the role of GTP-binding protein 8 could open doors to potential therapeutic strategies. Its involvement in fundamental cellular processes suggests that targeting this protein could offer novel approaches for treating diseases where these processes are dysregulated.