Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
Q8N4E4
UPID:
PDCL2_HUMAN
Alternative names:
-
Alternative UPACC:
Q8N4E4; A8MWA2; B9ZVQ9
Background:
Phosducin-like protein 2, encoded by the gene symbol Q8N4E4, plays a crucial role in cellular processes through its involvement in the modulation of intracellular signaling pathways. This protein, by virtue of its unique structure and function, has become a focal point of research in understanding cellular dynamics and regulatory mechanisms.
Therapeutic significance:
Understanding the role of Phosducin-like protein 2 could open doors to potential therapeutic strategies. Its pivotal role in cellular signaling pathways suggests that it could be a key target for drug discovery efforts aimed at modulating cellular functions for therapeutic benefits.