Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
Q8N8L6
UPID:
ARL10_HUMAN
Alternative names:
-
Alternative UPACC:
Q8N8L6
Background:
ADP-ribosylation factor-like protein 10 plays a crucial role in cellular processes, including intracellular trafficking and signal transduction. Its unique structure and function position it as a key player in maintaining cellular homeostasis and regulating protein transport.
Therapeutic significance:
Understanding the role of ADP-ribosylation factor-like protein 10 could open doors to potential therapeutic strategies. Its pivotal role in cellular functions highlights its potential as a target for drug discovery, aiming to modulate its activity for therapeutic benefits.