Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q8N987
UPID:
NECA1_HUMAN
Alternative names:
Neuronal calcium-binding protein 1
Alternative UPACC:
Q8N987; Q6NUS7; Q96AZ7; Q9HBW8
Background:
N-terminal EF-hand calcium-binding protein 1, also known as Neuronal calcium-binding protein 1, plays a crucial role in calcium signaling. This protein, identified by the accession number Q8N987, is pivotal in regulating various cellular processes through its ability to bind calcium ions. Its unique structure, characterized by the EF-hand motif, allows for a high degree of specificity and affinity towards calcium, making it an essential player in neuronal activity.
Therapeutic significance:
Understanding the role of N-terminal EF-hand calcium-binding protein 1 could open doors to potential therapeutic strategies. Its involvement in calcium signaling pathways offers a promising avenue for the development of novel treatments targeting neurological disorders.