Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q8WUN7
UPID:
UBTD2_HUMAN
Alternative names:
Dendritic cell-derived ubiquitin-like protein; Ubiquitin-like protein SB72
Alternative UPACC:
Q8WUN7; Q8TDQ3
Background:
Ubiquitin domain-containing protein 2, also known as Dendritic cell-derived ubiquitin-like protein and Ubiquitin-like protein SB72, plays a pivotal role in cellular processes. Its unique ubiquitin domain suggests involvement in protein degradation pathways, a critical function for maintaining cellular homeostasis.
Therapeutic significance:
Understanding the role of Ubiquitin domain-containing protein 2 could open doors to potential therapeutic strategies. Its involvement in fundamental cellular processes makes it a promising target for drug discovery, aiming to address diseases through novel mechanisms.