Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q8WWF6
UPID:
DNJB3_HUMAN
Alternative names:
-
Alternative UPACC:
Q8WWF6
Background:
DnaJ homolog subfamily B member 3 plays a crucial role in cellular processes as a co-chaperone for Hsp70 proteins, specifically in male germ cells and during the haploid stages of development. Its involvement in protein folding, assembly, and translocation underscores its importance in maintaining cellular homeostasis.
Therapeutic significance:
Understanding the role of DnaJ homolog subfamily B member 3 could open doors to potential therapeutic strategies. Its pivotal function in cell development and stress response highlights its potential as a target for therapeutic intervention in reproductive health and stress-related conditions.