Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q8WWM9
UPID:
CYGB_HUMAN
Alternative names:
Histoglobin; Stellate cell activation-associated protein
Alternative UPACC:
Q8WWM9; Q541Y7; Q8N2X5
Background:
Cytoglobin, identified by its unique accession number Q8WWM9, is known for its alternative names Histoglobin and Stellate cell activation-associated protein. This protein is speculated to play a crucial role in protecting cells under oxidative stress conditions and may be pivotal in intracellular oxygen storage or transfer.
Therapeutic significance:
Understanding the role of Cytoglobin could open doors to potential therapeutic strategies. Its involvement in cellular protection and oxygen regulation highlights its importance in maintaining cellular health and resilience.