Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q96A23
UPID:
CPNE4_HUMAN
Alternative names:
Copine IV; Copine-8
Alternative UPACC:
Q96A23; D3DNC5; Q8TEX1
Background:
Copine-4, also known as Copine IV or Copine-8, is identified as a probable calcium-dependent phospholipid-binding protein. This protein is believed to play a pivotal role in calcium-mediated intracellular processes, which are crucial for the normal functioning of cells.
Therapeutic significance:
Understanding the role of Copine-4 could open doors to potential therapeutic strategies. Its involvement in calcium-mediated processes suggests its potential impact on cellular functions, making it a target of interest in drug discovery.