Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q96L94
UPID:
SNX22_HUMAN
Alternative names:
-
Alternative UPACC:
Q96L94; Q8WUS9; Q9H844
Background:
Sorting nexin-22 plays a crucial role in intracellular trafficking, a process vital for cellular function and integrity. It specifically interacts with membranes containing phosphatidylinositol 3-phosphate, a lipid signaling molecule, indicating its involvement in the regulation of membrane dynamics and signaling pathways.
Therapeutic significance:
Understanding the role of Sorting nexin-22 could open doors to potential therapeutic strategies. Its involvement in intracellular trafficking suggests it may influence various cellular processes, making it a target of interest in the development of treatments for diseases where cellular trafficking is disrupted.