Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q96RD6
UPID:
PANX2_HUMAN
Alternative names:
-
Alternative UPACC:
Q96RD6; B7Z684; Q96RD5; Q9UGX8
Background:
Pannexin-2 plays a crucial role as a structural component of gap junctions and hemichannels, facilitating cell-to-cell communication in various tissues. This protein's unique structure and function underscore its importance in maintaining cellular homeostasis and signaling.
Therapeutic significance:
Understanding the role of Pannexin-2 could open doors to potential therapeutic strategies. Its pivotal function in cellular communication highlights its potential as a target for modulating physiological and pathological processes.