Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q99719
UPID:
SEPT5_HUMAN
Alternative names:
Cell division control-related protein 1; Peanut-like protein 1
Alternative UPACC:
Q99719; O15251; Q96MY5
Background:
Septin-5, also known as Cell division control-related protein 1 and Peanut-like protein 1, is a filament-forming cytoskeletal GTPase. Its similarity to other proteins suggests a role in cytokinesis and platelet secretion, highlighting its importance in cellular division and function.
Therapeutic significance:
Understanding the role of Septin-5 could open doors to potential therapeutic strategies. Its involvement in critical cellular processes underscores its potential as a target for drug discovery, aiming to modulate cellular division and secretion mechanisms.