Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q9BSJ2
UPID:
GCP2_HUMAN
Alternative names:
Gamma-ring complex protein 103 kDa; Spindle pole body protein Spc97 homolog
Alternative UPACC:
Q9BSJ2; B4DM18; B7ZKL8; F5H4E0; F5H4L0; O43632; Q5VWX7
Background:
Gamma-tubulin complex component 2, also known as Gamma-ring complex protein 103 kDa or Spindle pole body protein Spc97 homolog, plays a pivotal role in microtubule nucleation at the centrosome. This protein is essential for proper neuronal migration, highlighting its significance in the central nervous system's development.
Therapeutic significance:
The protein is linked to a disorder characterized by developmental delay, microcephaly, and seizures, among other symptoms. Understanding the role of Gamma-tubulin complex component 2 could open doors to potential therapeutic strategies for treating these neurological conditions.