Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q9BUA6
UPID:
MYL10_HUMAN
Alternative names:
Myosin light chain 2, lymphocyte-specific; Precursor lymphocyte-specific regulatory light chain
Alternative UPACC:
Q9BUA6
Background:
Myosin regulatory light chain 10, also known as Myosin light chain 2, lymphocyte-specific, plays a pivotal role in muscle contraction and motility. This protein, encoded by the gene with the accession number Q9BUA6, is integral to the function of myosin in muscle and non-muscle cells, acting as a regulatory component. Its alternative names, including Precursor lymphocyte-specific regulatory light chain, highlight its specific expression and function in lymphocytes.
Therapeutic significance:
Understanding the role of Myosin regulatory light chain 10 could open doors to potential therapeutic strategies. Its unique expression in lymphocytes suggests a specialized function that, once fully elucidated, may offer novel insights into muscle contraction disorders and lymphocyte-related diseases.