Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q9BYN8
UPID:
RT26_HUMAN
Alternative names:
28S ribosomal protein S13, mitochondrial; 28S ribosomal protein S26, mitochondrial
Alternative UPACC:
Q9BYN8; Q96Q58
Background:
The Small ribosomal subunit protein mS26, also known as 28S ribosomal protein S13 and S26, mitochondrial, plays a crucial role in the mitochondrial ribosome. It is involved in the synthesis of proteins within the mitochondria, essential for cellular energy production and metabolic processes. The protein's alternative names highlight its significance in the mitochondrial ribosomal function, underscoring its contribution to the complex machinery of protein synthesis.
Therapeutic significance:
Understanding the role of Small ribosomal subunit protein mS26 could open doors to potential therapeutic strategies. Its pivotal function in protein synthesis within mitochondria suggests that insights into its operation and regulation could lead to breakthroughs in treating diseases linked to mitochondrial dysfunction.