Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q9BYV6
UPID:
TRI55_HUMAN
Alternative names:
Muscle-specific RING finger protein 2; RING finger protein 29
Alternative UPACC:
Q9BYV6; B3KRC0; B3KRJ3; Q53XX3; Q8IUD9; Q8IUE4; Q96DV2; Q96DV3; Q9BYV5
Background:
Tripartite motif-containing protein 55, also known as Muscle-specific RING finger protein 2 or RING finger protein 29, plays a crucial role in regulating gene expression and protein turnover in muscle cells. Its unique structure and function position it as a key player in muscle cell biology.
Therapeutic significance:
Understanding the role of Tripartite motif-containing protein 55 could open doors to potential therapeutic strategies. Its involvement in muscle cell regulation highlights its potential as a target for treating muscle-related disorders.