Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q9H0C1
UPID:
ZMY12_HUMAN
Alternative names:
-
Alternative UPACC:
Q9H0C1; Q5VUS6; Q8TC87; Q96M51
Background:
Zinc finger MYND domain-containing protein 12 plays a crucial role in the regulation of gene expression through its involvement in chromatin remodeling and transcriptional regulation. Its unique structure, characterized by the presence of a MYND-type zinc finger domain, suggests a specific function in binding to other proteins or DNA, thereby influencing cellular processes.
Therapeutic significance:
Understanding the role of Zinc finger MYND domain-containing protein 12 could open doors to potential therapeutic strategies. Its involvement in fundamental cellular mechanisms makes it a promising target for drug discovery, aiming to modulate gene expression patterns implicated in various diseases.