Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
Q9H1K6
UPID:
TLRN1_HUMAN
Alternative names:
Mesoderm development candidate 1
Alternative UPACC:
Q9H1K6
Background:
Talin rod domain-containing protein 1, also known as Mesoderm development candidate 1, is an actin-binding protein. It plays a crucial role in cell proliferation, migration, and invasion, particularly in cancer cells. Its ability to regulate these processes suggests an oncogenic function, highlighting its importance in cancer biology.
Therapeutic significance:
Understanding the role of Talin rod domain-containing protein 1 could open doors to potential therapeutic strategies. Its involvement in key cellular processes makes it a promising target for drug discovery efforts aimed at controlling cancer cell behavior.