Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q9HD15
UPID:
SRA1_HUMAN
Alternative names:
Steroid receptor RNA activator protein
Alternative UPACC:
Q9HD15; Q6NVU9; Q8IXM1; Q9HD13; Q9HD14
Background:
Steroid receptor RNA activator 1, alternatively known as Steroid receptor RNA activator protein, plays a pivotal role in cellular processes. It functions as a transcriptional coactivator, enhancing steroid receptor-mediated transactivation both ligand-independently and dependently. This protein is crucial in cellular proliferation, differentiation, and apoptosis, suggesting its involvement in tumorigenesis.
Therapeutic significance:
Understanding the role of Steroid receptor RNA activator 1 could open doors to potential therapeutic strategies. Its involvement in cellular proliferation, differentiation, and apoptosis highlights its potential as a target in cancer therapy.