Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q9P013
UPID:
CWC15_HUMAN
Alternative names:
-
Alternative UPACC:
Q9P013; B2RC17; Q05BV9; Q05DM1; Q9UI29
Background:
Spliceosome-associated protein CWC15 homolog plays a crucial role in pre-mRNA splicing as part of the spliceosome. It is a key component of the PRP19-CDC5L complex, essential for activating pre-mRNA splicing. Additionally, it contributes to the splicing of U12-type introns, highlighting its importance in RNA processing.
Therapeutic significance:
Understanding the role of Spliceosome-associated protein CWC15 homolog could open doors to potential therapeutic strategies.