Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q9UBC5
UPID:
MYO1A_HUMAN
Alternative names:
Brush border myosin I; Myosin I heavy chain
Alternative UPACC:
Q9UBC5; Q9UQD7
Background:
Unconventional myosin-Ia, also known as Brush border myosin I or Myosin I heavy chain, plays a crucial role in cellular mechanics by directing the movement of organelles along actin filaments. This protein's unique function is pivotal in maintaining cellular structure and facilitating intracellular transport.
Therapeutic significance:
Understanding the role of Unconventional myosin-Ia could open doors to potential therapeutic strategies. Its involvement in cellular transport and structure maintenance highlights its importance in cellular functionality and health.