Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q9UDW1
UPID:
QCR9_HUMAN
Alternative names:
Complex III subunit 9; Complex III subunit X; Cytochrome c1 non-heme 7 kDa protein; Ubiquinol-cytochrome c reductase complex 7.2 kDa protein
Alternative UPACC:
Q9UDW1; B5MCM5; Q9T2V6
Background:
Cytochrome b-c1 complex subunit 9, also known as Complex III subunit 9, plays a pivotal role in the mitochondrial electron transport chain, crucial for oxidative phosphorylation. This protein is a component of the ubiquinol-cytochrome c oxidoreductase, facilitating electron transfer from ubiquinol to cytochrome c, and is instrumental in proton translocation across the mitochondrial inner membrane.
Therapeutic significance:
Understanding the role of Cytochrome b-c1 complex subunit 9 could open doors to potential therapeutic strategies.