Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q9UDX4
UPID:
S14L3_HUMAN
Alternative names:
Tocopherol-associated protein 2
Alternative UPACC:
Q9UDX4; E7EN74; E9PE57; Q495V8; Q495W0; Q495W1
Background:
SEC14-like protein 3, also known as Tocopherol-associated protein 2, is identified as a probable hydrophobic ligand-binding protein. Its primary role appears to be in the transport of hydrophobic ligands, including tocopherol (Vitamin E), squalene, and phospholipids, which are crucial for various biological processes.
Therapeutic significance:
Understanding the role of SEC14-like protein 3 could open doors to potential therapeutic strategies. Its involvement in the transport of essential hydrophobic molecules suggests a foundational role in cellular health and disease prevention.