Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our high-tech, dedicated method is applied to construct targeted libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
It includes comprehensive molecular simulations of the catalytic and allosteric binding pockets and the ensemble virtual screening accounting for their conformational mobility. In the case of designing modulators, the structural changes induced by reaction intermediates are taken into account to leverage activity and selectivity.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q9ULI2
UPID:
RIMKB_HUMAN
Alternative names:
N-acetyl-aspartylglutamate synthetase B; Ribosomal protein S6 modification-like protein B
Alternative UPACC:
Q9ULI2; B7Z834; D3DUV2; Q8N4P4; Q8WTW6
Background:
Beta-citrylglutamate synthase B, also known as N-acetyl-aspartylglutamate synthetase B and Ribosomal protein S6 modification-like protein B, plays a crucial role in the synthesis of beta-citryl-L-glutamate and N-acetyl-L-aspartyl-L-glutamate, with a preference for the former. This enzyme's activity is pivotal in the metabolism of specific amino acids.
Therapeutic significance:
Understanding the role of Beta-citrylglutamate synthase B could open doors to potential therapeutic strategies. Its involvement in amino acid metabolism highlights its importance in maintaining cellular health and offers a promising avenue for exploring novel treatments.