Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q9Y2R5
UPID:
RT17_HUMAN
Alternative names:
28S ribosomal protein S17, mitochondrial
Alternative UPACC:
Q9Y2R5; Q86X15
Background:
Small ribosomal subunit protein uS17m, also known as 28S ribosomal protein S17, mitochondrial, plays a crucial role in the mitochondrial ribosome. It is involved in the synthesis of proteins within mitochondria, essential for cellular energy production and metabolic processes.
Therapeutic significance:
Understanding the role of Small ribosomal subunit protein uS17m could open doors to potential therapeutic strategies. Its pivotal function in protein synthesis within mitochondria highlights its importance in cellular metabolism and energy production.