Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
Q9Y388
UPID:
RBMX2_HUMAN
Alternative names:
-
Alternative UPACC:
Q9Y388; A8K9Z0; Q5JY82; Q9Y3I8
Background:
RNA-binding motif protein, X-linked 2 plays a crucial role in pre-mRNA splicing, specifically as a component of the activated spliceosome. It is instrumental in the splicing of U12-type introns, which are rare and have a distinct set of spliceosomal components.
Therapeutic significance:
Understanding the role of RNA-binding motif protein, X-linked 2 could open doors to potential therapeutic strategies.