Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our top-notch dedicated system is used to design specialised libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
The procedure entails thorough molecular simulations of the catalytic and allosteric binding pockets, accompanied by ensemble virtual screening that factors in their conformational flexibility. When developing modulators, the structural modifications brought about by reaction intermediates are factored in to optimize activity and selectivity.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q9Y680
UPID:
FKBP7_HUMAN
Alternative names:
23 kDa FK506-binding protein; FK506-binding protein 7; Rotamase
Alternative UPACC:
Q9Y680; Q4ZG70; Q6V3B2; Q86U65; Q96DA4; Q9Y6B0
Background:
Peptidyl-prolyl cis-trans isomerase FKBP7, also known as 23 kDa FK506-binding protein, FK506-binding protein 7, and Rotamase, plays a crucial role in protein synthesis. It accelerates the folding of proteins, a fundamental process for cellular function and integrity.
Therapeutic significance:
Understanding the role of Peptidyl-prolyl cis-trans isomerase FKBP7 could open doors to potential therapeutic strategies. Its pivotal function in protein folding highlights its importance in maintaining cellular health and presents an opportunity for drug discovery.